Changing in the production of anticancer drugs (vinblastine and vincristine) in Catharanthus roseus (L.) G. Don by potassium and ascorbic acid treatments

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Changing in the production of anticancer drugs (vinblastine and vincristine) Catharanthus roseus (L.) G. Don by potassium ascorbic acid treatments | Neda Sahi, Akbar Mostajeran, Mustafa Ghanadian Agricultural Journals

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Mutation breeding in Catharanthus roseus (L.) G. Don: An Overview

Induced mutagenesis is best approach for creation of genetic variability but most of interest is paid towards crop plants with only a few exceptions. But even widely used medicinal plants could receive a little attention in this direction. Catharanthus roseus is an important plant medicinal plant yielding antihypertensive alkaloid ajmalcine and anticancerous alkaloid vincristine and vinblastine...

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Effect of Chromium on Antioxidant Potential of Catharanthus roseus Varieties and Production of Their Anticancer Alkaloids: Vincristine and Vinblastine

Catharanthus roseus (L.) G. Don, a medicinal plant, has a very important place in the traditional as well as modern pharmaceutical industry. Two common varieties of this plant rosea and alba are named so because of pink and white coloured flowers, respectively. This plant comprises of about 130 terpenoid indole alkaloids and two of them, vincristine and vinblastine, are common anticancer drugs....

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Induction and Flow Cytometry Identification of Tetraploids from Seed-Derived Explants through Colchicine Treatments in Catharanthus roseus (L.) G. Don

The tetraploid plants of Catharanthus roseus (L.) G. Don was obtained by colchicine induction from seeds explants, and the ploidy of the plants was identified by flow cytometry. The optimal treatment is 0.2% colchicine solution treated for 24 hours, and the induction rate reaches up to 30%. Comparing with morphological characteristics and growth habits between tetraploids and the control, we fo...

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Cytogenetic characterization and genome size of the medicinal plant Catharanthus roseus (L.) G. Don

BACKGROUND AND AIMS Catharanthus roseus is a highly valuable medicinal plant producing several terpenoid indole alkaloids (TIAs) with pharmaceutical applications, including the anticancer agents vinblastine and vincristine. Due to the interest in its TIAs, C. roseus is one of the most extensively studied medicinal plants and has become a model species for the study of plant secondary metabolism...

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Antidiabetic and antioxidant properties of alkaloids from Catharanthus roseus (L.) G. Don.

Catharanthus roseus (L.) G. Don is a herbal plant traditionally used by local populations in India, South Africa, China and Malaysia to treat diabetes. The present study reports the in vitro antioxidant and antidiabetic activities of the major alkaloids isolated from Catharanthus roseus (L.) G. Don leaves extract. Four alkaloids--vindoline I, vindolidine II, vindolicine III and vindolinine IV--...

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ژورنال

عنوان ژورنال: Plant Soil and Environment

سال: 2022

ISSN: ['1805-9368', '1214-1178']

DOI: https://doi.org/10.17221/121/2021-pse